N C C A M: The National Center for Complementary and Alternative Medicine

At the National Institutes of Health NIH…Turning Discovery Into Health

Follow NCCAM: Subscribe to our email update Subscribe to the NCCAM RSS feed Follow NCCAM on TwitterRead our disclaimer about external links Follow NCCAM on FacebookRead our disclaimer about external links

Horse Chestnut

Keywords: 

buckeye, Spanish chestnut, chronic venous insufficiency

Common Names: 

horse chestnut, buckeye, Spanish chestnut

Latin Name: 

Aesculus hippocastanum

Horse chestnut
© Steven Foster

On this page:

Introduction

This fact sheet provides basic information about horse chestnut—common names, uses, potential side effects, and resources for more information. Horse chestnut trees are native to the Balkan Peninsula (for example, Greece and Bulgaria), but grow throughout the Northern Hemisphere. Although horse chestnut is sometimes called buckeye, it should not be confused with the Ohio or California buckeye trees, which are related but not the same species.

What Horse Chestnut Is Used For

  • For centuries, horse chestnut seeds, leaves, bark, and flowers have been used for a variety of conditions and diseases.
  • Horse chestnut seed extract has been used to treat chronic venous insufficiency (a condition in which the veins do not efficiently return blood from the legs to the heart). This condition is associated with varicose veins, pain, ankle swelling, feelings of heaviness, itching, and nighttime leg cramping.
  • The seed extract has also been used for hemorrhoids.

Top

How Horse Chestnut Is Used

Horse chestnut seed extract standardized to contain 16 to 20 percent aescin (escin), the active ingredient, is the most commonly used form. Topical preparations have also been used.

Top

What the Science Says

  • Studies have found that horse chestnut seed extract is beneficial in treating chronic venous insufficiency. There is also preliminary evidence that horse chestnut seed extract may be as effective as wearing compression stockings.
  • There is not enough scientific evidence to support the use of horse chestnut seed, leaf, or bark for any other conditions.

Top

Side Effects and Cautions

Top

Sources

  • Horse chestnut. Natural Medicines Comprehensive Database Web site. Accessed at www.naturaldatabase.com on September 8, 2009.
  • Horse chestnut. Natural Standard Database Web site. Accessed at www.naturalstandard.com on September 8, 2009.
  • Horse chestnut seed extract. In: Blumenthal M, Goldberg A, Brinckman J, eds. Herbal Medicine Expanded Commission E Monographs. Newton, MA: Lippincott Williams & Wilkins; 2000:201–204.

Top

For More Information

NCCAM Clearinghouse

The NCCAM Clearinghouse provides information on NCCAM and complementary health practices, including publications and searches of Federal databases of scientific and medical literature. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners.

Toll-free in the U.S.: 
1-888-644-6226
TTY (for deaf and hard-of-hearing callers): 
1-866-464-3615

CAM on PubMed®

Your literature search will be automatically limited to the complementary and alternative medicine (CAM) subset of PubMed.

Office of Dietary Supplements (ODS)

ODS seeks to strengthen knowledge and understanding of dietary supplements by evaluating scientific information, supporting research, sharing research results, and educating the public. Its resources include publications and the International Bibliographic Information on Dietary Supplements database.

NIH National Library of Medicine's MedlinePlus

NCCAM Publication No.: 
D321
Created: 
May 2006
Updated: 
June 2010

Top